EIF4A1 and glioblastoma: Interestingly, in the TCGA (The Cancer Genome Atlas) GBM dataset, we realized that the patients with a CD44High signature tended to show higher expressions of the genes that encoded the proteins of the intracellular targets of BSH-polyR (eIF4E, eIF4A, eRF3, and eIF4G) (Figure 8C).