The results of studies by Chen et al. on the role and effects of recombinant rainbow trout (rt) pro-IGF1-E-peptides’ action in human cancer cell lines, indicated anticancer activities of the recombinant rtEa4-peptide [human Eb peptide (hEB) analogue] on cultured human BC cell lines (MCF7, MDA-MB-231, ZR751 cells) [168,169]. This evidence concerns the gene IGF1 and cancer.