However, tumor cell‐derived cytokines (e.g., VEGF, IL10, and TGF‐β) and inhibitory factors (e.g., galectin‐1, indoleamine 2,3‐dioxygenase, and lipid mediators) are ready to suppress DC maturation and T‐cell activation [54, 55]. This evidence concerns the gene TGFB1 and neoplasm.