From the findings we can suggest that the expression pattern base on genotype is associated with HPV status thus indicating that person with HPV 16 infection and homozygous proline residues compare to Arg residues are more susceptible to p53 degradation, though the report is contradictory to the findings of Storey et al. [32] who have reported that persons homozygous for arginine at residue 72 of p53 (p53Arg) are about seven times more prone to invasive cervical cancer than those who carry at least one proline at that position (p53Pro). This evidence concerns the gene TP53 and cervical carcinoma.