Accordingly, CX3CR1 expression on CD8 T cells, endothelial production of CX3CL1, and T cell CX3CL1-mediated adhesion and chemotaxis are all increased in people with coronary artery disease, and attenuated following six months of statin therapy, which decreases risk of CVD events [44]. The gene discussed is CX3CL1; the disease is coronary artery disorder.