In podocyte cell models, mutated TBC1D8B results in defective trafficking pathways [52]; (2) more than 50 mutations of TBC1D24 are now associated with a range of inherited neurological disorders, including myoclonic epilepsy, epileptic encephalopathy, and the DOORS syndrome (deafness, onychodystrophy, osteodystrophy, mental retardation, and seizures). This evidence concerns the gene TBC1D24 and deafness.