GRHL2 and oral cavity squamous cell carcinoma: Furthermore, the oncogenic role of GRHL2 is observed in hepatocellular carcinoma (Tanaka et al., 2008), esophageal cancer (Shao et al., 2017), oral squamous cell carcinoma (Kang et al., 2009; Chen et al., 2016), and colorectal carcinoma (Quan et al., 2014, 2015).