Since it has been suggested that multiple genes are associated with pathogenesis of autoimmune disorders and some autoimmune diseases might share the same genetic background of co-occurrence within individuals and families, the aim of the study was to assess the association of chosen single nucleotide polymorphisms of IL2RA, IFIH1, and CTLA-4 genes in the group of Polish children with AITDs and in children with T1D. The gene discussed is IFIH1; the disease is type 1 diabetes mellitus.