Although the survival analyses showed that there was no significant differences between the different expression levels of HER2 in tumor tissues, which is in accordance with other studies (23, 24), it seemed that the prognoses of patients with 2+/3+ HER2 expression in tumor tissues were relatively better when compared with their counterparts, which corresponded to the result of xenotransplanted animal tumor models. Here, ERBB2 is linked to neoplasm.