CDKL3 and neoplasm: Our results from 46 paired tumor and normal adjacent tissues indicated that CDKL3 and ATG5 were, respectively, high-expressed in 32 of 46 (69.56%) and 41 of 46 (89.13%) cases of ESCC, which was statistically higher than that in the adjacent non-tumor tissue (Figure 7A and Table 1).