Univariate logistic regression assessment pointed out that the T stage, lymph node metastasis, AJCC stage, and EI24 expression were related to the OS of ESCC patients, and multivariate logistic regression assessment posited that decreased EI24 expression and advanced AJCC stage were shown to be independent predictors of worse survival (Table 2). This evidence concerns the gene EI24 and esophageal squamous cell carcinoma.