TWIST1 and colorectal carcinoma: miR-17-92a is an exosomal miR cluster widely regarded as a protumoral miR (44), whereas miR-885-5p is overexpressed during CRC liver metastasis by inhibiting the cytoplasmic polyadenylation element-binding protein 2 (CPEB2), resulting in TWIST upregulation, which then leads to EMT.