According to the KEGG analysis for mRNAs co-expressed with five lncRNAs, as expected, we observed that the majority of the enriched pathways manifested the immunomodulatory functions, and the top five significantly enriched pathways involved in cytokine–cytokine receptor interaction, PD–L1 expression, and PD−1 checkpoint pathway in cancer, Th1 and Th2 cell differentiation, viral protein interaction, with cytokine and cytokine receptor as well as T cell receptor signaling pathway (Figure 6C). Here, CD274 is linked to cancer.