Multivariate Cox survival analyses including gender (female vs. male), age status (<18 vs. ≥18 months), INSS stage (INSS 2/3/4S vs. INSS 4), MYCN amplification (non-amplified vs. amplified), COG risk status (low risk vs. high risk), ploidy (hyperploid vs. diploid), histology type (favorable vs. unfavorable), differentiation (differentiating vs. poorly differentiated), MKI (low/intermediate vs. high), and pathology subtype (ganglioneuroblastoma vs. NB) as covariates were performed to evaluate the independent prognostic role of the lncRNA signature (Figure 7B). The gene discussed is MYCN; the disease is neuroblastoma.