Furthermore, PD-L1 was related to tumor grade of UTUC (High vs. Low, OR = 3.56, 95% CI = 1.82-6.97, <i>P</i> = 0.000) and invasive depth (pT3+pT4+pT2 vs. pT1+pTa/pTis, OR = 2.53, 95% CI = 1.07-5.96, <i>P</i> = 0.001). The gene discussed is CD274; the disease is renal pelvis/ureter urothelial carcinoma.