The results indicated that the tumor hallmarks, such as P53 pathway (NES = 1.720, P = 0.013), P13K/AKT/mTOR signaling (NES = 1.811, P = 0.008), DNA repair (NES = 2.050, P < 0.001), and MTORC1 signaling (NES = 1.894, P = 0.006) (Figures 3C,D) were enriched in MC2 subtype. This evidence concerns the gene AKT1 and neoplasm.