In line with our findings, prior studies have shown constitutive activation and overexpression of p65, a major marker of canonical NF-κB signaling, in many human epithelial cancers including ovarian, and have also demonstrated increasing expression of p65 along the continuum of borderline ovarian tumors to invasive carcinomas [43, 48–54]. The gene discussed is NFKB1; the disease is invasive carcinoma.