While pre-clinical in vitro and in vivo studies have demonstrated a variety of mechanisms by which non-canonical NF-κB signaling may contribute to ovarian cancer carcinogenesis and progression, no studies to date have reported associations between non-canonical NF-κB transcription factors and ovarian cancer clinical prognosis [31, 32, 34, 35]. The gene discussed is NFKB1; the disease is ovarian carcinoma.