MAPT and Alzheimer disease: Receiveroperating characteristic (ROC) curve analysis performed between groups showedbiomarker cutoff values as follows: Ab42, 532.5 pg./mL (sensitivity 100%,specificity 87.5%); tau 100 pg./mL (sensitivity 84.5%, specificity 87.5%); p-tau,26.5 pg./mL (sensitivity 69.2%, specificity 87.5%); Ab42/p-tau, 20.5 pg./mL(sensitivity 92.3%, specificity 87.5%); AD CSF profile 1.350 pg./mL (sensitivity100%, specificity 100%).