APOE and Alzheimer disease: They alsodetected a higher frequency of APOE4 in AD cases (ε3/ε4genotype presented an OR=1.738; 95%CI 1.233-2.450; p=0.0016, and ε4/ε4 genotypeshowed an OR=10.568; 95%CI 3.197-34.932; p=0.0001).