They alsodiscovered a positive association between the GAB2 GGgenotype and AD (OR=1.8; 95%CI 1.01-3.18; p=0.021), which was higher inAPOE ε4 carriers (OR=5.08; 95%CI 1.45-18.98; p=0.006).Finally, the authors identified an association between theGSK3B GG genotype and AD (OR=2.48; 95%CI 1.19-5.20;p=0.018), which was higher in the absence of the ε4 allele. Here, GAB2 is linked to Alzheimer disease.