In the blood and Cerebrospinal fluid (CSF) of patients with coronavirus pneumonia, Interleukin-6(IL-6), C-reactive protein (CRP), Interleukin-1(IL-1), Tumor Necrosis Factor (TNF) and other proinflammatory factors are all increased to varying degrees [15], among with high levels of IL-6 are strongly related to progressive neurological dysfunction, neurodegeneration and cognitive impairment [16]. This evidence concerns the gene TNF and Cognitive impairment.