ADIPOQ and diabetes mellitus: In the subgroup with newly diagnosed diabetes, there was a significant reduction in serum adiponectin in the placebo group (− 0.48 μg/mL [− 0.8, − 0.16], p = 0.004), whereas there was no change in the anthocyanins group (− 0.02 μg/mL [− 0.33, 0.3], p = 0.917), and the net change in adiponectin between the two groups was statistically significant (0.46 μg/mL [0.03, 0.90], p = 0.038) (Fig. 2c).