The top 10 genes were KIF18B, BIRC5, CDC20, CDCA5, MKI67, TPX2, NCAPG, MAD2L1, NEK2, and KIF4A. KIF18B had the highest MCC value and is deemed as the hub gene of ccRCC as a result. Here, BIRC5 is linked to nonpapillary renal cell carcinoma.