Five selection signature genes (UCP2, UCP3, ZMYND11, SCAPER, and TSHR) are contributing to the phenotype term of “body weight” or “global developmental delay.” Our results suggested that thyroid-stimulating hormone receptor (TSHR) is one of the co-selective signature genes between the CM and the DE, XH, NJ, and YC breeds (Figure 6). The gene discussed is UCP3; the disease is Global developmental delay.