KCNIP4 and asthma: Additionally, one of the genes that contains a significant SNP identified in this study, KCNQ5, is in the same family as one of the candidate genes, KCNIP4, thus lending further evidence to the potential importance of this gene family, which helps regulate airway smooth muscle cell contraction and is important in asthma (Valverde et al., 2011; Kocmalova et al., 2015).