Furthermore, absence of CD8 T cells also resulted in increased ZIKV replication in the CNS of WT mice, when these were challenged early (week 1) after priming; still, the ability of WT mice to produce Abs secured these a better fate as would be expected from our earlier demonstration that virus-specific antibodies are present in the circulation already 6–7 days post infection (35). The gene discussed is CD8A; the disease is infection.