Genome-wide association study (GWAS) data have indicated that EoE shares some susceptible genetic loci with other manifestations of the atopic march, including polymorphisms in the signal transducer and activator of transcription 6 gene (STAT6) and TSLP (35). The gene discussed is STAT6; the disease is multinucleated neurons-anhydramnios-renal dysplasia-cerebellar hypoplasia-hydranencephaly syndrome.