In Salmonella Typhimurium infection, B cell-specific MyD88 signaling is essential for optimal development of IL-10-producing CD19+CD138+ B cells, especially in early stages of infection, and via MyD88 signaling, CD19+CD138+ B cells inhibit three key types of cells: neutrophils, natural killer cells, and inflammatory T cells (36). Here, SDC1 is linked to infection.