CD8A and tuberculosis: In contrast to the results with healthy donors, in PBMC collected from TB patients, the MFI of TNF-α-producing CD8+ T-cells induced by WT lipids was 3-fold higher than in non-stimulated or Δmce1 lipids-stimulated PBMC, suggesting distinct roles of Mtb lipids in activating T lymphocytes subpopulations in healthy and TB subjects.