In Table 1, 21 are the recombinant proteins curing human diseases (Figure 1A), including those for treating cancer (interleukin, interferon, Tumor Necrosis Factor Alpha-TNF-α), cardiovascular pathologies (streptokinase, hirudin), and metabolic or auto-immune disorders (glucagon, phenylalanine ammonia-lyase, tendamistat). This evidence concerns the gene TNF and immune system disorder.