In addition, NK cells present in the lung are often enriched in CD56dim/CD16bright cells but recently, during the HCMV infection, a novel adaptive killer-cell Ig-like receptor (KIR)+/NKG2C+/NK cell subset with a CD49a+/CD56bright/CD16- tissue-resident (tr) NK cell phenotype (Figure 2) has been identified in human lungs (Cong and Wei, 2019; Dogra et al., 2020). Here, KLRC2 is linked to cytomegalovirus infection.