Complete and partial EMT in cancer is executed by EMT-activating transcription factors, including SNAIL, TWIST, and ZEB families, which regulate all stages of cancer progression from initiation, primary tumor growth, invasion, metastasis, to colonization, as well as resistance to therapy (Brabletz et al., 2018; Pastushenko and Blanpain, 2019). The gene discussed is SNAI1; the disease is cancer.