For example, Lu and co-workers identified 100 mg·kg-1 of EO as the most effective dose that produced significant decrease in severity of bronchitis symptoms, less inflammatory cells infiltration, and reduced airway mucin secretion in rat chronic bronchitis caused by lipopolysaccharide (LPS) (Lü Xiaoqin et al., 2004). This evidence concerns the gene MUC5AC and bronchial disorder.