Finally, we discovered that resveratrol-FMT mice showed significantly lower kidney mRNA levels of TNF-α, IFN-γ, IL-6, and IL-1β compared to control-FMT recipients (Figure 5H), suggesting that reduced inflammation by resveratrol-modified fecal microbial community may be a key mechanism for protecting the renal function of DN. The gene discussed is IL1B; the disease is liver dysplastic nodule.