Quercetin (i.p.)supplementation for 3 days prior to OVA challenge reduced airway eosinophilia and AHR for more than 50%, while effectively lowering eosinophil peroxidase (EPO) activity and reducing pulmonary Th2/ILC2 markers GATA-3, IL-4 and IL-5, and enhancing Th1 marker T-bet (Park et al., 2009). Here, IL4 is linked to Increased total eosinophil count.