In a murine model for OVA-induced asthma, i.p. lycopene injections of sensitized mice for 3 days before OVA challenge lowered AHR and eosinophilia for 50%, while normalizing IL-4 levels in the BALF and increasing IFN-γ, indicating a shift in T-cell response (Lee et al., 2008). Here, IL4 is linked to Increased total eosinophil count.