Cell division cycle 5-like (Cdc5l) protein has been shown to promote hTERT expression and colorectal tumor growth (Li et al., 2017), while metastasis biomarker Park7/DJ-1 is known to promote colon cancer by stimulating Wnt-β-catenin signaling (Zhou et al., 2018). Here, CDC5L is linked to malignant colon neoplasm.