HTR2C and epilepsy: Recently, there has been some evidence of the involvement of the serotonergic system (including different aliases of HTR2C such us 5-HT1A, 5-HT2C, 5-HT3) in the pathomechanism of epilepsy and its contribution on provoking spontaneous and recurring seizures either by increasing or decreasing neuronal excitability (Isaac, 2005; Panczyk et al., 2015).