The validation analysis indicated that the nine persons from the four trios who presented the polyphasic phenotype, indeed had the inframe deletion at SYT14. However, only seven out of 17 JME patients who presented polyphasia had the SYT14 polymorphism (41.17%), seven out of 16 (43.75%) relatives (five from the trios) and four out of 14 (28.57%) from the group of controls. This evidence concerns the gene SYT14 and juvenile myoclonic epilepsy.