In cell culture experiments, tau oligomers applied to media were taken up into the nuclei of human neuroblastoma cells and stem cell-derived cortical neurons (Usenovic et al., 2015; Wegmann et al., 2016; Evans et al., 2018; Karikari et al., 2019a; Puangmalai et al., 2020). The gene discussed is MAPT; the disease is neuroblastoma.