Furthermore, because of the possibility of intraocular injections to deliver the vector close to the target retina, quantitative evaluations for monitoring therapeutic responses through OCT and electrophysiologic testing, and the rapid disease progression in SCA7, RNAi and ASOs targeting ataxin-7 may be a feasible treatment for SCA7 retinal degeneration. The gene discussed is ATXN7; the disease is spinocerebellar ataxia 7.