(1) MD with foveal damage: stimuli presented at the PRL elicited strong responses in the occipital pole while stimuli presented at the fovea elicited little or no response. (2) MD with fovea residual function: stimulation of the fovea produced weak activation of the occipital pole. Stimulation of PRL produced no activation. (3) Control participants: no activation of investigated areas for stimuli presented to peripheral retina (corresponding to the matched MD participant’s PRL). This evidence concerns the gene PRL and Menkes disease.