Other significant clusters include translocation of SLC2A4 to plasma membrane, protein processing in the ER, Nop56p-associated pre-rRNA complex, nucleocytoplasmic transport, Emerin complex 52, C complex spliceosome, DGCR8 multiprotein complex, H2AX complex, telomere maintenance, ACTB-ANP32A-C1QBP-PSMA1-PTMA-PSMA1 complex, DHX9-ADAR-vigilin-DNA-PK-Ku antigen complex, and systemic lupus erythematosus (Fig. 2). This evidence concerns the gene PRKDC and systemic lupus erythematosus.