MSLN and lymphoma: Today, many CRISPR-Cas9-mediated clinical trials for treatment of cancers including relapsed or refractory leukemia and lymphoma (NCT03398967 and NCT03166878), Acute Lymphoblastic Leukemia/Lymphoma and non-Hodgkin Lymphoma (NCT03690011), relapsed or refractory B-cell malignancies (NCT04035434), relapsed or refractory multiple myeloma (NCT04244656), non-small cell lung cancer (NCT02793856), mesothelin-positive solid multiple tumors (NCT03545815 and NCT03747965), and EBV-associated malignancies (NCT03044743) are under evaluation [66].