BMP7 and neoplasm: In order to determine whether MAPK14 downregulation in TILs depended on BMP7 secretion in the tumor microenvironment, we evaluated the expression of MAPK14 and MAPK14-regulated cytokines and chemokines in TILs isolated from BMP7-knockdown tumors and control tumors treated with IgG or anti-PD1.