MAPT and Alzheimer disease: In the second cohort, we found a strong correlation between p-tau T217 and p-tau T181 (figure 5A, r = 0.941, 95% CI 0.896, 0.967, p < 0.0001) and between p-tau T217 and t-tau (figure 5B, r = 0.902, 95% CI 0.829, 0.944, p < 0.0001) in AD.