Mycobacteriosis, staphylococcosis, and candidiasis can be driven by monogenic inborn errors of interferon-γ (IFN-γ), interleukin-6 (IL-6), and IL-17A and IL-17F, respectively, or they can be driven by their genetically driven autoimmune phenocopies, with the production of neutralizing autoantibodies (auto-Abs) against these cytokines (1–8). The gene discussed is IL6; the disease is Candidiasis, Invasive.