Recent studies have shown that evaluation of three proliferation markers (ki67, MCM2, and geminin) together can provide valuable information about the proliferative status of cells in some cancers.3, 8, 18 So far, geminin and the MCM2/ki67 and geminin/ki67 ratios have not been evaluated in cutaneous SCC and BCC of the head and neck. The gene discussed is MKI67; the disease is cancer.