SLC25A38 and early-onset autosomal dominant Alzheimer disease: A study of another mechanism for curcumin in apoptosis investigated the effects of curcumin in appoptosin-induced apoptosis in SH-SY5Y cells, where appoptosin (SLC25A38) is a pro-apoptotic protein that is up-regulated in Alzheimer’s disease (AD) brains and promotes the pathological progress.