CYCS and neoplasm: Until now, several metallodrugs including cisplatin, carboplatin, oxaliplatin [55,122,123], Auoxo3 [92], Auoxo4, Au2phen [93], 4-PF6 [94], NAMI A [89], Ru(II)(η6-p-cymene) [90], Di-Ruthenium-1[95], [Ru(bpy)2dppz]2+, [Ru(phen)2dppz]2+, and [Ru(bpy)3]2+ [96], as well as non-metallic drugs including DOX [21], curcumin [124], and cytochrome C [62], have been encapsulated in ferritin cavity to improve their bioavailability, tumor-selectivity, and cellular permeability and reduce the toxicity to normal cells.