Furthermore, the CD8 score was highly correlated with the tumor immune cytolytic activity score (CYT), which was defined by granzyme A and perforin expression, in the TNBC of both TCGA and METABRIC cohorts (Figure 4C; r = 0.650 and = 0.792, respectively, both p < 0.01). Here, PRF1 is linked to neoplasm.