REN and basal cell carcinoma: KEGG pathway analysis revealed that ‘long-term depression’, ‘platelet activation’, ‘renin secretion’, ‘gap junction’, and ‘circadian entrainment’ were upregulated only in HIV-1 infected MDMs (Figure 6B and Table S6.1); the downregulated miRNA-targeted mRNAs were mainly involved in ‘basal cell carcinoma’, ‘human papillomavirus infection’, ‘wnt signaling pathway’, and ‘melanogenesis’ (Figure 6B and Table S6.1).