C2 and colorectal carcinoma: Interestingly, five glycoproteins, namely AZGP1, ITH1, ITH2, SERPINC1 and SERPING2 were significantly expressed only in plasma samples of CRC patients with non-metastasis, while 11 glycoproteins consisting of A1BG, A2M, C2, CFB, CPN2, HP, ORM1, SERPINA1, SERPINA6, TTR, and VTN were significantly expressed only in the patients with metastasis.